CMF - Studies

SPINALOGIC™

CMF treatment associated with

97%

lumbar fusion compared to 62% patients that received no stim.⁴

Peer reviewed results show

that smokers treated with CMF were reported to have higher fusion Rates than smokers that did not receive stimulation.

Fusion Rates

Effectiveness of combined magnetic field bone growth stimulation on lumbar spinal fusion outcomes: a single center retrospective analysis comparing combined magnetic field to no stimulation.*

FUSION RATES	TREATED WITH CMF™	TREATED WITH NO STIM
Overall	97% (n=343)	62% (n=309)¹
Smokers	94%	61%²
55+ years	97%	58%³

1. p 0.00001 2. p = 0.000032 3. p 0.00001

Ryaby, J.T., et al., The Role of Insulin-like Growth Factor in Magnetic Field Regulation of Bone Formation, Bioelectrochemistry and Bioenergetics, 35: 87-91, 1994

Fitzsimmons RJ, Ryaby JT, Magee FP, Baylink DJ. IGF-II receptor number is increased in TE-85 osteosarcoma cells by combined magnetic fields. J Bone Miner Res. 1995 May;10(5):812-9.

Charles Sfeir, DDS, PhD, Lawrence Ho, Bruce A. Doll, DDS, PhD, Kodi Azari, MD, and Jeffrey O. Hollinger, DDS, PhD. Fractrue Repair. Bone Regeneration and Repair, Biology and Clinical Applications. 2005, XII, 398p

Raiszadeh, Ramin, et al. "Effectiveness of combined magnetic field bone growth stimulation on lumbar spinal fusion outcomes: a single center retrospective analysis comparing combined magnetic field to no-stimulation." International Journal of Research in Orthopaedics 6.3 (2020): 1. A retrospective study that utilized radiographic fusion criteria, included data from 4 surgeons, consisted of a heterogenous patient population and had minimum 6 months follow up.

Wu N, Lee YC, Segina D, Murray H, Wilcox T, Boulanger L. The economic impact of US patients With fracture non-union, Orthopedic Research and Reviews, 2013; 5:21–33

[PMA 910066] Phillips, Mark, et al. "The Use of Combined Magnetic Field Treatment for Fracture Nonunion: A Prospective Observational Study." Journal of Long-Term Effects of Medical Implants 26.3 (2016).

NASS coverage reccomendations: https://www.spine.org/coverage

Linovitz, Raymond J., et al. "Combined magnetic fields accelerate and increase spine fusion: a double-blind, randomized, placebo controlled study." Spine 27.13 (2002): 1383-1388.

Mcleod, Kenneth J., and C. T. Rubin. "The effect of low-frequency electrical fields on osteogenesis." J Bone Joint Surg Am 74.6 (1992): 920-9.

[P910066 / S005] Phillips, Mark, et al. "Use of Combined Magnetic Field Treatment for Fracture Nonunion." Journal of Long-Term Effects of Medical Implants 26.3 (2016).

Joel Russell, Sheila Sprague, Sam Harper, Michelle Green & Mohit Bhandari (2021) An early cost analysis of magnetic bone growth stimulation in England, Expert Review of Pharmacoeconomics & Outcomes Research, DOI: 10.1080/14737167.2021.1920402

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CMF - Studies

New Published Data

SPINALOGIC™

CMF treatment associated with

lumbar fusion compared to 62% patients that received no stim.⁴

Peer reviewed results show

Fusion Rates

CMF - Studies

New Published Data

SPINALOGIC™

CMF treatment associated with

lumbar fusion compared to 62% patients that received no stim.4

Peer reviewed results show

Fusion Rates

lumbar fusion compared to 62% patients that received no stim.⁴